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KMID : 0351619770180020323
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Kyungpook Medical Journal
1977 Volume.18 No. 2 p.323 ~ p.327
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Changes in Serum Immunoglobulins Following Major Operations
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金圭太/Kim, Kyu Tae
金松明/李光淑/李聖行/Kim, Song Myung/Lee, Kwang Sook/Lee, Sung Haing
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Abstract
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Serum total protein, electrophoresic fractions and Immunoglobulins levels in serum were measured immediately before and 12 days after msjor operation in 9 patients, including four tumor patients. Immunoglobulins were determined. by radial immuno-diffusion, while serum. protein electrophoresis was carried out on cellulose acetate strips.
Postoperatively the serum albumin level and the hemoglobin were reduced, but serum total protein did not change. An increase in serum Immunoglobulins (IgG, IgA and IgM) was found in most patient 12 days after operation. TlZere was no significant correlation between immunoglobulin level in serum and duration of anesthesia. The patients with the cancer showed significant decrease in serum total protein after operation, but r_o significant difference in serum immunoglobulin levels was found.
The patients with the postoperative complication tended to have low serum. total protein. levela before and following operation, but a decrease in immunoglobulia levels was found only before operation.
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